Utilization of deep learning in early detection of lung cancer through CT Scan images: thematic analysis in medical diagnosis innovation
Keywords:
Deep Learning, CT scan, Lung Cancer, Early Detection, Medical Diagnosis, Convolutional Neural NetworkAbstract
Early detection of lung cancer is a major challenge in the global healthcare system, particularly due to the often asymptomatic nature of the disease in its early stages. CT imaging (Computed Tomography) has become a key tool in early diagnosis, but it still faces challenges in terms of accuracy, interpretation time, and reliance on radiological expertise. This study aims to analyze the use of deep learning technology in increasing the effectiveness of lung cancer detection through CT scan images. This study uses a systematic literature review approach and thematic analysis of a number of popular deep learning models such as CNN (Convolutional Neural Network), U-Net, and ResNet. The results show that deep learning can significantly improve the sensitivity and specificity of diagnosis, while speeding up the detection process. The implications of this study open up great opportunities for the transformation of cancer diagnostic systems that are more efficient, accurate, and affordable.
References
Ardila, D., Kiraly, A. P., Bharadwaj, S., Choi, B., Reicher, J. J., Peng, L., ... & Tse, D. (2019). End-to-end lung cancer screening with three-dimensional deep learning on low-dose chest computed tomography. Nature Medicine, 25(6), 954–961. https://doi.org/10.1038/s41591-019-0447-x
Chen, X., Xu, Y., Zhang, X., Jin, X., Liu, Y., & Tang, Y. (2022). A hybrid deep learning framework for lung nodule classification using U-Net and CNN. Computers in Biology and Medicine, 142, 105234. https://doi.org/10.1016/j.compbiomed.2022.105234
Khosravan, N., Bagci, U. (2019). S4ND: Single-Shot Single-Scale Lung Nodule Detection. MICCAI 2018: Medical Image Computing and Computer Assisted Intervention, 794–802. https://doi.org/10.1007/978-3-030-00934-2_90
Li, Q., Cao, Y., Liu, H., & Wu, J. (2021). Lung cancer detection using ResNet-50 with transfer learning. IEEE Access, 9, 8822–8832. https://doi.org/10.1109/ACCESS.2021.3050116
McKinney, S. M., Sieniek, M., Godbole, V., Godwin, J., Antropova, N., Ashrafian, H., ... & Suleyman, M. (2020). International evaluation of an AI system for breast cancer screening. Nature, 577(7788), 89–94. https://doi.org/10.1038/s41586-019-1799-6
Nguyen, H. P., Pham, T. Q., Do, H. T., & Tran, L. M. (2023). Automated detection of lung cancer using DenseNet and deep transfer learning. Journal of Medical Imaging and Health Informatics, 13(2), 412–418.
Park, S., Lee, S., Kim, J., & Yoon, C. (2022). Deep learning-based LSTM algorithm for lung cancer detection using time-series CT images. Biomedical Signal Processing and Control, 73, 103451. https://doi.org/10.1016/j.bspc.2021.103451
Wang, J., Li, X., & Wang, Y. (2020). Lung cancer detection using 2D convolutional neural networks with high accuracy. IEEE Transactions on Industrial Informatics, 16(4), 2446–2455. https://doi.org/10.1109/TII.2019.2936340
Zhao, Y., Chen, J., Yu, Y., & Liang, G. (2021). EfficientNet-based detection of lung cancer using low-dose CT images. Artificial Intelligence in Medicine, 116, 102089. https://doi.org/10.1016/j.artmed.2021.102089
Setio, A. A. A., Traverso, A., de Bel, T., Berens, M. S., van den Bogaard, C., Cerello, P., ... & van Ginneken, B. (2017). Validation, comparison, and combination of algorithms for automatic detection of pulmonary nodules in computed tomography images: The LUNA16 challenge. Medical Image Analysis, 42, 1–13. https://doi.org/10.1016/j.media.2017.06.015
Armato, S. G., McLennan, G., Bidaut, L., McNitt-Gray, M. F., Meyer, C. R., Reeves, A. P., ... & Clarke, L. P. (2011). The lung image database consortium (LIDC) and image database resource initiative (IDRI): A completed reference database of lung nodules on CT scans. Medical Physics, 38(2), 915–931. https://doi.org/10.1118/1.3528204
Esteva, A., Kuprel, B., Novoa, R. A., Ko, J., Swetter, S. M., Blau, H. M., & Thrun, S. (2017). Dermatologist-level classification of skin cancer with deep neural networks. Nature, 542(7639), 115–118. https://doi.org/10.1038/nature21056
Hosny, A., Parmar, C., Quackenbush, J., Schwartz, L. H., & Aerts, H. J. (2018). Artificial intelligence in radiology. Nature Reviews Cancer, 18(8), 500–510. https://doi.org/10.1038/s41571-018-0016-5
Shen, W., Zhou, M., Yang, F., Yang, C., & Tian, J. (2015). Multi-scale convolutional neural networks for lung nodule classification. Information Processing in Medical Imaging, 588–599. https://doi.org/10.1007/978-3-319-19992-4_46
Huang, G., Liu, Z., Van Der Maaten, L., & Weinberger, K. Q. (2017). Densely connected convolutional networks. In Proceedings of the IEEE conference on computer vision and pattern recognition (pp. 4700–4708). https://doi.org/10.1109/CVPR.2017.243.




